Article

Expansion of a neural crest gene signature following ectopic MYCN expression in sympathoadrenal lineage cells in vivo

2024-04-04

Abstract excerpt

Neural crest cells (NCC) are multipotent migratory stem cells which originate from the neural tube during early vertebrate embryogenesis. NCC give rise to a variety of cell types within the developing organism, including neurons and glia of the sympathetic nervous system. It has been suggested that failure in correct NCC differentiation leads to several diseases, including neuroblastoma (NB). During normal NCC dev...

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Literature Corpus work: 029c11a8-2750-5c03-8f1a-0583a69d843b
DOI: 10.1101/2024.04.03.587923

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