Article
Neuroblastoma and Its Zebrafish Model.
Advances in experimental medicine and biology - 1 Jan 2016
Zhu Shizhen, Thomas Look A
Abstract excerpt
Neuroblastoma, an important developmental tumor arising in the peripheral sympathetic nervous system (PSNS), accounts for approximately 10 % of all cancer-related deaths in children. Recent genomic analyses have identified a spectrum of genetic alterations in this tumor. Amplification of the MYCN oncogene is found in 20 % of cases and is often accompanied by mutational activation of the ALK (anaplastic lymphoma...
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