Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neuroblastoma: When differentiation goes awry

18 Aug 2022

Abstract excerpt

Neuroblastoma is a leading cause of cancer-related death in children. Accumulated data suggest that differentiation arrest of the neural-crest-derived sympathoadrenal lineage contributes to neuroblastoma formation. The developmental arrest of these cell types explains many biological features of the disease, including its cellular heterogeneity, mutational spectrum, spontaneous regression, and response to drugs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Neuroblastoma Research and Treatments
Share to Zebrafish Biomedical Research Applications

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35985323
DOI: 10.1016/j.neuron.2022.07.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neuroblastoma: When differentiation goes awryPMID 35985323Read ↗

Neuroblastoma—A Neural Crest Derived Embryonal MalignancySemantic proximity Read ↗

NeuroblastomaSemantic proximity Read ↗

Mechanisms involved in selecting and maintaining neuroblastoma cancer stem cell populations, and perspectives for therapeutic targetingSemantic proximity Read ↗

Chemoresistance, Cancer Stem Cells, and miRNA Influences: The Case for NeuroblastomaSemantic proximity Read ↗

Neuroblastoma: biological insights into a clinical enigma.Semantic proximity Read ↗

Recent advances in the developmental origin of neuroblastoma: an overviewSemantic proximity Read ↗

Molecular Basis and Clinical Features of NeuroblastomaSemantic proximity Read ↗

Neuroblastoma: Molecular Pathogenesis and TherapySemantic proximity Read ↗

Hijacking of Embryonic Programs by Neural Crest-Derived Neuroblastoma: From Physiological Migration to Metastatic DisseminationSemantic proximity Read ↗

Palbociclib releases the latent differentiation capacity of neuroblastoma cellsSemantic proximity Read ↗

Neuroblastoma: a clinical challenge and biologic puzzleSemantic proximity Read ↗

Neuroblastoma: A Tough Nut to Crack.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.