Article

Modelling prion-induced neurodegeneration in PrP transgenic Drosophila

2019-01-01

Abstract excerpt

The aim of my thesis was to develop and characterise PrP transgenic Drosophila melanogaster of various genotypes to study the process of prion-induced neurodegeneration in this model. Prion diseases are caused by the occurrence of an abnormally-folded form of PrP (PrPSc) protein that arises either from the environment as an acquired disease, from mutation in the PrP-coding gene as a genetic disease or sporadically...

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Literature Corpus work: 027001ce-b006-5429-9ad0-b4c679c7fd0e
DOI: 10.17863/cam.37641

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