Article
Transgenic analysis of prion diseases.
Molecular human reproduction - 1 Jun 1997
Moore R C, Melton D W
Abstract excerpt
Prion diseases are fatal transmissible neurological disorders afflicting a range of mammalian species. Although still controversial, a large body of data suggests that the causative agent may be composed entirely of a small glycoprotein. The brains of infected animals have accumulations of a path...
Topics
- Animals
- Cricetinae
- Disease Models, Animal
- Encephalopathy, Bovine Spongiform
- Humans
- Mice
- Mice, Knockout
- Mice, Transgenic
- Mutation
- Prion Diseases
- Prions
- Scrapie
- Species Specificity