Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transgenic analysis of prion diseases.

Molecular human reproduction - 1 Jun 1997

Moore R C, Melton D W

Abstract excerpt

Prion diseases are fatal transmissible neurological disorders afflicting a range of mammalian species. Although still controversial, a large body of data suggests that the causative agent may be composed entirely of a small glycoprotein. The brains of infected animals have accumulations of a pathogenic protease-resistant isoform (PrPsc) of a normal host-encoded glycoprotein, PrPc or prion protein. A number of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cricetinae
Share to Disease Models, Animal
Share to Mice

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Knockout

Share to Mice, Transgenic

Share to Mutation

Share to Prions

Share to Species Specificity

Source

Identifiers

PMID: 9239743
DOI: 10.1093/molehr/3.6.529

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transgenic analysis of prion diseases.PMID 9239743Read ↗

Transgenetic investigations of prion diseases of humans and animals.Semantic proximity Read ↗

Experimental Models of Inherited PrP Prion Diseases.Semantic proximity Read ↗

Genetics of prions.Semantic proximity Read ↗

Neurodegenerative illness in transgenic mice expressing a transmembrane form of the prion protein.Semantic proximity Read ↗

A transgenic model of a familial prion disease.Semantic proximity Read ↗

Modelling prion-induced neurodegeneration in PrP transgenic DrosophilaSemantic proximity Read ↗

Review: contribution of transgenic models to understanding human prion disease.Semantic proximity Read ↗

PrP knock-out and PrP transgenic mice in prion research.Semantic proximity Read ↗

Molecular genetics of human prion diseases.Semantic proximity Read ↗

An Amino Acid Substitution Found in Animals with Low Susceptibility to Prion Diseases Confers a Protective Dominant-Negative Effect in Prion-Infected Transgenic Mice.Semantic proximity Read ↗

GFP-tagged prion protein is correctly localized and functionally active in the brains of transgenic mice.Semantic proximity Read ↗

Genetic and infectious prion diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.