Article
Prions.
Cold Spring Harbor perspectives in biology - 1 Jan 2011
Colby David W, Prusiner Stanley B
Abstract excerpt
The discovery of infectious proteins, denoted prions, was unexpected. After much debate over the chemical basis of heredity, resolution of this issue began with the discovery that DNA, not protein, from pneumococcus was capable of genetically transforming bacteria (Avery et al. 1944). Four decades later, the discovery that a protein could mimic viral and bacterial pathogens with respect to the transmission of...
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