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Elevated <i>Plasmodium falciparum</i> sexual conversion in HbAC and HbAS red blood cells in naturally infected malaria patients

2025-11-15

Abstract excerpt

<h4>ABSTRACT</h4> Malaria transmission relies on the differentiation of asexual parasites into gametocytes, a process initiated by sexual conversion (SC). Mutations in the host hemoglobin beta (HBB) gene are known to influence parasite growth and disease outcome, yet their impact on SC remains unclear. We investigated the effect of HBB mutant genotypes on Plasmodium falciparum SC and humoral immunity in individu...

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Identifiers and source

Literature Corpus work
025d35ff-701f-5a13-93b9-c422ac51dbb4
DOI
10.1101/2025.11.15.688532
Open publication

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Elevated <i>Plasmodium falciparum</i> sexual conversion in HbAC and HbAS red blood cells in naturally infected malaria patientsDOI 10.1101/2025.11.15.688532
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