Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasmodium falciparum sexual differentiation in malaria patients is associated with host factors and GDV1-dependent genes

13 May 2019

Abstract excerpt

Abstract Plasmodium sexual differentiation is required for malaria transmission, yet much remains unknown about its regulation. Here, we quantify early gametocyte-committed ring (gc-ring) stage, P. falciparum parasites in 260 uncomplicated malaria patient blood samples 10 days before maturation to transmissible stage V gametocytes using a gametocyte conversion assay (GCA). Seventy six percent of the samples have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement system in diseases
Share to Malaria Research and Control
Share to Mosquito-borne diseases and control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31086187
DOI: 10.1038/s41467-019-10172-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasmodium falciparum sexual differentiation in malaria patients is associated with host factors and GDV1-dependent genesPMID 31086187Read ↗

The transcriptome of circulating sexually committed Plasmodium falciparum ring stage parasites forecasts malaria transmission potentialSemantic proximity Read ↗

Dissecting the role of PfAP2-G in malaria gametocytogenesisSemantic proximity Read ↗

PfAP2-G2 Is Associated to Production and Maturation of Gametocytes in Plasmodium falciparum via Regulating the Expression of PfMDV-1Semantic proximity Read ↗

GDV1 induces sexual commitment of malaria parasites by antagonizing HP1-dependent gene silencingSemantic proximity Read ↗

A single valine to leucine switch disrupts Plasmodium falciparum AP2-G DNA binding and reveals GDV1's role in ap2-g activation.Semantic proximity Read ↗

The PfAP2-G2 transcription factor is a critical regulator of gametocyte maturationSemantic proximity Read ↗

The PfAP2‐G2 transcription factor is a critical regulator of gametocyte maturationSemantic proximity Read ↗

Specific expression and export of the Plasmodium falciparum Gametocyte EXported Protein-5 marks the gametocyte ring stageSemantic proximity Read ↗

Conditional expression of PfAP2-G for controlled massive sexual conversion in Plasmodium falciparumSemantic proximity Read ↗

Regulators of male and female sexual development are critical for the transmission of a malaria parasiteSemantic proximity Read ↗

Number and proportion of P. <i>falciparum</i> gametocytes vary from acute infection to chronic parasite carriage despite unaltered sexual commitment rateSemantic proximity Read ↗

Plasmodium falciparum Gametocyte Development 1 (Pfgdv1) and Gametocytogenesis Early Gene Identification and Commitment to Sexual DevelopmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.