Article

Chemical proteomics reveals regulation of bile salt hydrolases via oxidative post-translational modifications

2025-12-14

Abstract excerpt

The gut microbiome is the vast, diverse ecosystem of microorganisms that inhabits the human intestines and provides numerous essential functions for the host. One such key role is the metabolism of primary bile acids that are biosynthesized in the host liver into a plethora of secondary bile acids produced by gut bacteria. These metabolites serve as both antimicrobial and chemical signaling agents within the host....

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Literature Corpus work: 025740e9-4f79-5498-9714-ca8e1bc7df81
DOI: 10.64898/2025.12.11.693737

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