Article

Bile salt hydrolase/aminoacyltransferase shapes the microbiome

2022-10-10

Abstract excerpt

<title>Abstract</title> <p>Bile acids (BAs) are steroid detergents in bile that contribute to the absorption of fats and fat-soluble vitamins while shaping the gut microbiome due to their antimicrobial properties. Recently, a novel mechanism of BA metabolism by the gut microbiota was identified involving conjugation with various amino acids. Here, we show this unique biochemistry is mediated by bile salt hydrolas...

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Literature Corpus work: 2633722f-7122-5ed7-9a87-97eacfa6f4b7
DOI: 10.21203/rs.3.rs-2050406/v1

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