Article

EHF is essential for epidermal and colonic epithelial homeostasis and suppresses <i>Apc</i> -initiated colonic tumorigenesis

2021-03-02

Abstract excerpt

<h4>Background</h4> Ets homologous factor (EHF) is a member of the epithelial-specific Ets (ESE) transcription factors. EHF is specifically expressed in epithelial tissues, however its role in development and epithelial homeostasis is largely uncharacterized. <h4>Methods</h4> We generated a novel mouse strain in which the Ets DNA binding domain (exon 8) of Ehf was flanked by loxP sites ( Ehf Lox/Lox ). To inact...

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Literature Corpus work: 0248f1fa-ff77-5d3c-9428-8fe11125ad8a
DOI: 10.1101/2021.03.01.433470

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