Article

K-means clustering of hyperpolarised<sup>13</sup>C-MRI identifies intratumoural perfusion/metabolism mismatch in renal cell carcinoma as best predictor of highest grade

2024-05-08

Abstract excerpt

<h4>Purpose</h4> Conventional renal mass biopsy approaches are inaccurate, potentially leading to undergrading. This study explored using hyperpolarised [1- 13 C]pyruvate MRI (HP 13 C-MRI) to identify the most aggressive areas within the tumour of patients with clear cell renal cell carcinoma (ccRCC). <h4>Experimental design</h4> Six patients with ccRCC underwent presurgical HP 13 C-MRI and conventional contrast-e...

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Literature Corpus work: 02233956-9a00-5697-9858-d01690295c0c
DOI: 10.1101/2024.05.06.24306829

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