Article

Jamestown Canyon virus rapidly adapts to mosquito cells through multiple M segment mutations

2026-06-27

Abstract excerpt

<h4>ABSTRACT</h4> Jamestown Canyon virus (JCV) is a mosquito-borne orthobunyavirus with an unusually broad host and vector range. Despite increasing mosquito-to-human spillover, the viral determinants governing host adaptation remain poorly defined. We examined changes in JCV replication during serial passage in mosquito cells and sought to link adaptive changes in viral fitness to specific genetic mutations. In...

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Identifiers and source

Literature Corpus work: 021150d1-4505-5a55-a3ef-9a8bd480059b
DOI: 10.64898/2026.06.22.733793

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