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Characterization of mosquito-adapted West Nile virus

17 Jun 2008

Abstract excerpt

West Nile virus (WNV), a mosquito-borne flavivirus, has significantly expanded its geographical and host range since its 1999 introduction into North America. The underlying mechanisms of evolution of WNV and other arboviruses are still poorly understood. Studies evaluating virus adaptation and fitness in relevant in vivo systems are largely lacking. In order to evaluate the capacity for host-specific adaptation...

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PMID: 18559933
DOI: 10.1099/vir.0.2008/000893-0

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