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Article

Host alternation of chikungunya virus increases fitness while restricting population diversity and adaptability to novel selective pressures.

Journal of virology - 1 Jan 2011

Coffey Lark L, Vignuzzi Marco

Abstract excerpt

The mechanisms by which RNA arboviruses, including chikungunya virus (CHIKV), evolve and maintain the ability to infect vertebrate and invertebrate hosts are poorly understood. To understand how host specificity shapes arbovirus populations, we studied CHIKV populations passaged alternately betwe...

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Identifiers

PMID: 21047966
DOI: 10.1128/JVI.01918-10
PMCID: PMC3020036

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21047966-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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