Article
High genomic stability of Andes virus following successive passage in vivo in Syrian hamsters.
Journal of virology - 19 Aug 2025
Warner Bryce M, Prévost Jérémie, Tailor Nikesh, Deschambault Yvon, Sloan Angela, Allarie Julina, Klassen Levi, Frost Kathy, Booth Stephanie, Audet Jonathan, Soule Geoff, Safronetz David
Abstract excerpt
Andes virus (ANDV) is a South American hantavirus that causes hantavirus cardiopulmonary syndrome (HCPS), a severe respiratory infection with a case fatality rate as high as 40%. A critical model for studying HCPS is the Syrian hamster model, which faithfully recapitulates key aspects of the disease. Recent studies have shown that strains of ANDV from different origins, i.e., from rodent or human hosts, can...
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