Article

Transiently depleting RNPS1 leads to perdurable changes in alternative splicing

2018-06-12

Abstract excerpt

<h4>ABSTRACT</h4> While robust regulatory mechanisms are expected to control the production of splice variants that confer distinct functions, a low level of stochasticity may be tolerated. To investigate stringency of regulation, we followed changes in the splicing of 192 alternative cassette exons after growth of cancer-derived HCT116 cells and embryonic colonocytes. In both cell lines approximately 15% of alte...

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Identifiers and source

Literature Corpus work: 01fbe5d8-4892-553f-b067-12a318bd0b3b
DOI: 10.1101/344507

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