Article

TGF-β promotes microtube formation in glioblastoma through Thrombospondin 1

2021-02-22

Abstract excerpt

Microtubes (MTs), cytoplasmic extensions of glioma cells, are important cell communication structures promoting invasion and treatment resistance through network formation. MTs are abundant in chemoresistant gliomas, in particular glioblastomas (GBMs), while they are uncommon in chemosensitive IDH-mutant and 1p/19q co-deleted oligodendrogliomas. To identify potential signaling pathways involved in MT formation we...

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Literature Corpus work: 01f9bd04-5529-5d5f-904c-183fc5bac433
DOI: 10.1101/2021.02.22.431443

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