Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Massively Parallel Signature Sequencing and Bioinformatics Analysis Identifies Up-Regulation of TGFBI and SOX4 in Human Glioblastoma

19 Apr 2010

Abstract excerpt

BACKGROUND: A comprehensive network-based understanding of molecular pathways abnormally altered in glioblastoma multiforme (GBM) is essential for developing effective therapeutic approaches for this deadly disease. METHODOLOGY/PRINCIPAL FINDINGS: Applying a next generation sequencing technology, massively parallel signature sequencing (MPSS), we identified a total of 4535 genes that are differentially expressed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Developmental Biology and Gene Regulation
Share to Glioma Diagnosis and Treatment
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20419098
DOI: 10.1371/journal.pone.0010210

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Massively Parallel Signature Sequencing and Bioinformatics Analysis Identifies Up-Regulation of TGFBI and SOX4 in Human GlioblastomaPMID 20419098Read ↗

Comprehensively investigating the expression levels and the prognostic role of transforming growth factor beta-induced (TGFBI) in glioblastoma multiformeSemantic proximity Read ↗

DNA Methylation-based Diagnostic and Prognostic Biomarkers for GlioblastomaSemantic proximity Read ↗

The TGF-β Family in GlioblastomaSemantic proximity Read ↗

Enhanced Expression of TGFBI Promotes the Proliferation and Migration of Glioma CellsSemantic proximity Read ↗

Glioblastoma multiforme: insights into pathogenesis, key signaling pathways, and therapeutic strategiesSemantic proximity Read ↗

Overview of Transforming Growth Factor β Superfamily Involvement in Glioblastoma Initiation and ProgressionSemantic proximity Read ↗

Unveiling the Diagnostic and Prognostic potential of BMP Pathway and Hypoxia-inducible Factors in Glioblastoma MultiformeSemantic proximity Read ↗

SOCS3 is Related to Cell Proliferation in Neuronal Tissue: An Integrated Analysis of Bioinformatics and ExperimentsSemantic proximity Read ↗

Experimental validation of 5 in-silico predicted glioma biomarkersSemantic proximity Read ↗

Targeting NF-κB in glioblastoma: A therapeutic approachSemantic proximity Read ↗

Mir-21–Sox2 Axis Delineates Glioblastoma Subtypes with Prognostic ImpactSemantic proximity Read ↗

RUNX2 mediated epithelial mesenchymal transition induced by TGF beta and Smad signaling promotes malignant progression in gliomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.