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The conserved coordination of acyl-homoserine lactone and PqsE signaling defines the RhlR-dependent quorum-sensing network in <i>Pseudomonas aeruginosa</i> clinical isolates

2026-05-21

Abstract excerpt

<h4>ABSTRACT</h4> Quorum sensing (QS) enables Pseudomonas aeruginosa to coordinate virulence and biofilm formation through cell density-dependent signaling. In clinical isolates from patients with cystic fibrosis (pwCF), mutations in canonical QS systems such as lasR and rhlI often lead to altered signaling hierarchies that complicate our understanding of QS regulation during chronic infection. Here, we dissec...

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Literature Corpus work
5b208194-3654-5032-a90b-da9d840ce87e
DOI
10.64898/2026.05.21.726854
Open publication

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The conserved coordination of acyl-homoserine lactone and PqsE signaling defines the RhlR-dependent quorum-sensing network in <i>Pseudomonas aeruginosa</i> clinical isolatesDOI 10.64898/2026.05.21.726854
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