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Quorum sensing antiactivators constrain <i>Pseudomonas aeruginosa</i> RhlR activity

2025-11-01

Abstract excerpt

Pseudomonas aeruginosa , an opportunistic pathogen, uses a cell-cell communication system called quorum sensing (QS) to regulate gene expression in response to population density. P. aeruginosa QS involves, in part, two transcription factors, LasR and RhlR, that respond to N -acyl homoserine lactone (AHL) signals. Two proteins known as “antiactivators,” QteE and QslA, attenuate QS by inhibiting LasR, RhlR, or bo...

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Literature Corpus work
48e0c2a7-5215-5e84-bc39-80e3ede309dd
DOI
10.1101/2025.10.31.685934
Open publication

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Quorum sensing antiactivators constrain <i>Pseudomonas aeruginosa</i> RhlR activityDOI 10.1101/2025.10.31.685934
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