Article

Regression convolutional neural network models implicate peripheral immune regulatory variants in the predisposition to Alzheimer’s disease

2022-12-03

Abstract excerpt

<h4>ABSTRACT</h4> Alzheimer’s disease (AD) involves aggregation of amyloid β and tau, neuron loss, cognitive decline, and neuroinflammatory responses. Both resident microglia and peripheral immune cells have been associated with the immune component of AD. However, the relative contribution of resident and peripheral immune cell types to AD predisposition has not been thoroughly explored due to their similarity i...

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Literature Corpus work: 01f0e656-7215-5d1b-adc5-070e0e0a44fd
DOI: 10.1101/2022.12.02.518903

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