Article

Molecular evolution of <i>DNMT1</i> in vertebrates: duplications in marsupials followed by positive selection

2018-01-13

Abstract excerpt

DNA methylation is mediated by a conserved family of DNA methyltransferases (Dnmts). The human genome encodes five Dnmts: Dnmt1, Dnmt2, Dnmt3a, Dnmt3b and Dnmt3L. Despite their high degree of conservation among different species, genes encoding Dnmts have been duplicated and/or lost in multiple lineages throughout evolution, indicating that the DNA methylation machinery has some potential to undergo evolutionary c...

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Literature Corpus work: b4e91c69-7b9a-54df-a7ff-7dec22e43687
DOI: 10.1101/247643

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