Article

Functional cardiac consequences of β-adrenergic stress-induced injury in the <i>mdx</i> mouse model of Duchenne muscular dystrophy

2024-04-20

Abstract excerpt

<h4>ABSTRACT</h4> Cardiomyopathy is the leading cause of death in Duchenne muscular dystrophy (DMD), however, in the mdx mouse model of DMD, the cardiac phenotype differs from that seen in DMD-associated cardiomyopathy. Although some have used pharmacologic stress to enhance the cardiac phenotype in the mdx model, many methods lead to high mortality, variable cardiac outcomes, and do not recapitulate the struct...

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Literature Corpus work: 019595c5-136e-5608-a4f7-1be4b381d2a4
DOI: 10.1101/2024.04.15.589650

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