Article

Triphenyl phosphate is a selective PPARγ modulator that does not induce brite adipogenesis <i>in vitro</i> and <i>in vivo</i>

2019-05-03

Abstract excerpt

Triphenyl phosphate (TPhP) is an environmental PPARγ ligand, and growing evidence suggests that it is a metabolic disruptor. We have shown previously that the structurally similar ligand, tributyltin, does not induce brite adipocyte gene expression. Here, using in vivo and in vitro models, we tested the hypothesis that TPhP is a selective PPARγ ligand, which fails to induce brite adipogenesis. C57BL/6J male mice...

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Literature Corpus work: 015e6f25-0502-5463-876e-3535ea4a1a6c
DOI: 10.1101/626390

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