Article

2,4-Di-tert-butylphenol Induces Adipogenesis in Human Mesenchymal Stem Cells by Activating Retinoid X Receptors

2022-10-09

Abstract excerpt

<h4>ABSTRACT</h4> 2,4-di-tert-butylphenol (2,4-DTBP) is an important commercial antioxidant and a toxic natural secondary metabolite that has been detected in humans. However, there is scant information regarding its toxicological effects. Here we asked whether 2,4-DTBP is a potential obesogen. Using a human mesenchymal stem cell (MSC) adipogenesis assay, we found that exposure to 2,4-DTBP led to increased lipid...

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Literature Corpus work: 31c111cf-730a-571f-b32a-1b7231aee044
DOI: 10.1101/2022.10.08.511439

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