Article

Unraveling the stability landscape of mutations in the SARS-CoV-2 receptor-binding domain

2020-08-17

Abstract excerpt

<title>Abstract</title> <p>The interaction between the receptor-binding domain of the SARS-CoV-2 spike glycoprotein and the ACE2 enzyme is believed to be the entry point of the virus into various cells in the body, including the lungs, heart, liver, and kidneys. The current focus of several therapeutic design efforts explore attempts at affecting the binding interaction between the two proteins to limit the activ...

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Literature Corpus work: 014e7540-e2de-5080-93bb-48fa7a9274e5
DOI: 10.21203/rs.3.rs-59058/v1

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