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Understanding Mutations in Human SARS-CoV-2 Spike Glycoprotein: A Systematic Review & Meta-Analysis.

Viruses - 27 Mar 2023

Kumar Reetesh, Srivastava Yogesh, Muthuramalingam Pandiyan, Singh Sunil Kumar, Verma Geetika, Tiwari Savitri, Tandel Nikunj, Beura Samir Kumar, Panigrahi Abhishek Ramachandra, Maji Somnath, Sharma Prakriti, Rai Pankaj Kumar, Prajapati Dinesh Kumar, Shin Hyunsuk, Tyagi Rajeev K

Abstract excerpt

Genetic variant(s) of concern (VoC) of SARS-CoV-2 have been emerging worldwide due to mutations in the gene encoding spike glycoprotein. We performed comprehensive analyses of spike protein mutations in the significant variant clade of SARS-CoV-2, using the data available on the Nextstrain server. We selected various mutations, namely, A222V, N439K, N501Y, L452R, Y453F, E484K, K417N, T478K, L981F, L212I, N856K,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37112836
DOI: 10.3390/v15040856
PMCID: PMC10142771

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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