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Article

Unraveling the stability landscape of mutations in the SARS-CoV-2 receptor-binding domain.

Scientific reports - 28 Apr 2021

Smaoui Mohamed Raef, Yahyaoui Hamdi

Abstract excerpt

The interaction between the receptor-binding domain (RBD) of the SARS-CoV-2 spike glycoprotein and the ACE2 enzyme is believed to be the entry point of the virus into various cells in the body, including the lungs, heart, liver, and kidneys. The current focus of several therapeutic design efforts explores attempts at affecting the binding potential between the two proteins to limit the activity of the virus and...

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Share to Angiotensin-Converting Enzyme 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Spike Glycoprotein, Coronavirus

Source

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Identifiers

PMID: 33911163
DOI: 10.1038/s41598-021-88696-5
PMCID: PMC8080587

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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