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The Evolving Role of Zika Virus Envelope Protein in Viral Entry and Pathogenesis

6 Jun 2025

Abstract excerpt

Zika virus (ZIKV) was first discovered in Uganda's Zika Forest in 1947. The early African viruses posed little or no health risk to humans. Since then, ZIKV has undergone extensive genetic evolution and adapted to humans, and it now causes a range of human diseases, including neurologically related diseases in adults and congenital malformations such as microcephaly in newborns. This raises a critical question as...

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PMID: 40573410
DOI: 10.3390/v17060817

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