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Polarization of Macrophages in Tumor Microenvironment Using High-Throughput Single-Cell Metabolomics

2 Sept 2024

Abstract excerpt

Macrophages consist of a heterogeneous population of functionally distinct cells that participate in many physiological and pathological processes. They exhibit prominent plasticity by changing their different functional phenotypes represented by proinflammatory (M1) and anti-inflammatory (M2) in response to different environmental stimuli. Emerging evidence illustrates the importance of intracellular metabolic...

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PMID: 39221578
DOI: 10.1021/acs.analchem.4c02989

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