Article

Utility of animal models of Alzheimer's disease in food bioactive research

2021-03-01

Abstract excerpt

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by globally impaired cognition. AD research in animals has shown a substantial deficit in translational relevance. The most extensively used transgenic mouse models overexpress human genes associated with rare familial early-onset AD, which results in the formation of amyloid plaques. However, the most common form of AD (late-onset...

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Literature Corpus work: 008904b2-d771-51d9-8d72-111ca208d5f8
DOI: 10.31665/jfb.2020.13255

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