Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transgenic animals in Alzheimer's disease research.

Reviews in the neurosciences - 1 Jan 1999

Sturchler-Pierrat C, Sommer B

Abstract excerpt

Alzheimer's disease (AD) is a neurodegenerative disorder of the brain accounting for about 50-70% of the typical late onset cases of dementia. The pathological and diagnostic hallmarks of the disease are principally the presence of extracellular deposits called neuritic amyloid plaques and the intracellular aggregation of neurofibrillary tangles. In addition selective neuronal cell loss accompanied by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Amyloid beta-Peptides
Share to Amyloid beta-Protein Precursor

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Apolipoproteins E

Share to Mice, Transgenic

Share to Neurofibrillary Tangles

Share to Peptide Fragments

Share to Plaque, Amyloid

Source

Identifiers

PMID: 10356989
DOI: 10.1515/revneuro.1999.10.1.15

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transgenic animals in Alzheimer's disease research.PMID 10356989Read ↗

Insights into Alzheimer disease pathogenesis from studies in transgenic animal models.Semantic proximity Read ↗

Transgenic mouse models of Alzheimer's disease.Semantic proximity Read ↗

Transgenic animals relevant to Alzheimer’s diseaseSemantic proximity Read ↗

Insights on the Use of Transgenic Mice Models in Alzheimer’s Disease ResearchSemantic proximity Read ↗

Transgenic Mice as a Model for Alzheimers DiseaseSemantic proximity Read ↗

Transgenic mouse models of Alzheimer's disease: phenotype and application.Semantic proximity Read ↗

Rodent models for Alzheimer’s disease drug discoverySemantic proximity Read ↗

Transgenic mice and modeling Alzheimer's disease.Semantic proximity Read ↗

Relevance of Transgenic Mouse Models to Human Alzheimer DiseaseSemantic proximity Read ↗

Mice as models: Transgenic approaches and Alzheimer's diseaseSemantic proximity Read ↗

Animal models of Alzheimer's disease: Applications, evaluation, and perspectives.Semantic proximity Read ↗

Animal and Cellular Models of Alzheimer’s Disease: Progress, Promise, and Future ApproachesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.