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Article

Transgenic mouse models of Alzheimer's disease.

The Mount Sinai journal of medicine, New York - 1 Jan 2000

Elder Gregory A, Gama Sosa Miguel A, De Gasperi Rita

Abstract excerpt

Alzheimer's disease is the most common cause of senile dementia in the United States and Europe. At present, there is no effective treatment. Given the disease's prevalence and poor prognosis, the development of animal models has been a high research priority. Transgenic modeling has been pursued on the basis of the amyloid hypothesis and has taken advantage of mutations in the amyloid precursor protein and the...

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Identifiers

PMID: 20101721
DOI: 10.1002/msj.20159
PMCID: PMC2925685

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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