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Insights on the Use of Transgenic Mice Models in Alzheimer’s Disease Research

28 Feb 2024

Abstract excerpt

Alzheimer's disease (AD), the leading cause of dementia, presents a significant global health challenge with no known cure to date. Central to our understanding of AD pathogenesis is the β-amyloid cascade hypothesis, which underlies drug research and discovery efforts. Despite extensive studies, no animal models of AD have completely validated this hypothesis. Effective AD models are essential for accurately...

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PMID: 38474051
DOI: 10.3390/ijms25052805

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