Article

Germline Variants in Centromere Binding Protein 126 Predispose to Glioblastoma

2026-07-22

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. While only 5% of GBM cases arise in a familial context, the genetic basis of familial GBM remains unresolved in most affected clusters, suggesting that important susceptibility variants may reside outside recognized cancer-predisposition genes. Proband-based genomic studies of such families provid...

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Literature Corpus work: 007ea8a9-7105-57a6-9643-163bda26c108
DOI: 10.64898/2026.07.20.26358470

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