Article

Population-scale study of eRNA transcription reveals bipartite functional enhancer architecture

2018-09-27

Abstract excerpt

Enhancer RNAs (eRNA) are non-coding RNAs transcribed bidirectionally from active regulatory sequences. Their expression levels correlate with the activating potentials of the enhancers, but due to their instability, eRNAs have proven difficult to quantify in large scale. To overcome this, we use capped-nascent-RNA sequencing to efficiently capture the bidirectional initiation of eRNAs. We apply this in large scale...

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Literature Corpus work: 005ce44e-acc0-5253-91e7-d53668737c87
DOI: 10.1101/426908

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