Article

Integrated Quantitative Neuro-transcriptome Analysis of Several Brain Areas in Human Trisomy 21

2021-07-28

Abstract excerpt

<h4>Background: </h4> Although Down syndrome (DS) is a trisomy of chromosome 21 being the most frequent human chromosomal disorder mainly associated with variables dysfunctions. Objective In this context, we aimed to analyze and compare the disruption of transcriptome of several brain areas from individuals with DS and euploid controls as a new approach to consider a global systemic differential disruption of gen...

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Literature Corpus work: 0039bdfc-77d2-54d0-8b11-2ea9a9b61cfb
DOI: 10.21203/rs.3.rs-745690/v1

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