Article

SNPPar: identifying convergent evolution and other homoplasies from microbial whole-genome alignments

2020-07-10

Abstract excerpt

Homoplasic single nucleotide polymorphisms (SNPs) are considered important signatures of strong (positive) selective pressure, and hence of adaptive evolution for clinically relevant traits such as antibiotic resistance and virulence. Here we present a new tool, SNPPar, for efficient detection and analysis of homoplasic SNPs from large WGS datasets (>1,000 isolates and/or >100,000 SNPs). SNPPar takes as input a SN...

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Literature Corpus work: 00218585-20e6-588d-8a5e-f744683b0c3b
DOI: 10.1101/2020.07.08.194480

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