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Article

Evolution and diversity of clonal bacteria: the paradigm of Mycobacterium tuberculosis.

PloS one - 6 Feb 2008

Dos Vultos Tiago, Mestre Olga, Rauzier Jean, Golec Marcin, Rastogi Nalin, Rasolofo Voahangy, Tonjum Tone, Sola Christophe, Matic Ivan, Gicquel Brigitte

Abstract excerpt

BACKGROUND: Mycobacterium tuberculosis complex species display relatively static genomes and 99.9% nucleotide sequence identity. Studying the evolutionary history of such monomorphic bacteria is a difficult and challenging task. PRINCIPAL FINDINGS: We found that single-nucleotide polymorphism (SNP) analysis of DNA repair, recombination and replication (3R) genes in a comprehensive selection of M. tuberculosis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 18253486
DOI: 10.1371/journal.pone.0001538
PMCID: PMC2211405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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