Article

Rapid Kinetic Fingerprinting of Single Nucleic Acid Molecules by a FRET-based Dynamic Nanosensor

2021-04-06

Abstract excerpt

<h4>ABSTRACT</h4> Biofluids contain cell-free nucleic acids such as microRNAs (miRNAs) and circulating tumor-derived DNAs (ctDNAs) that have emerged as promising disease biomarkers. Conventional detection of these biomarkers by digital PCR and next generation sequencing, although highly sensitive, requires time-consuming extraction and amplification steps that increase the risk of sample loss and cross-contaminat...

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Literature Corpus work: 00202ede-d0c8-5947-928b-6fecb2e2f713
DOI: 10.1101/2021.04.06.438627

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