Article

Genetic Analysis of Factor VIII Gene Polymorphisms in Indian Populations for Hemophilia A Carrier Screening

2025-01-10

Abstract excerpt

<title>Abstract</title> <p>Background A deficiency of factor VIII (FVIII) and factor IX (FIX) causes hemophilia A (HA) and hemophilia B (HB), respectively. This X-linked recessive disorder involves mutations in the F8 gene at Xq28 for HA and at Xq27 for HB on the X chromosome. These disorders, which cause complications with coagulation and prolonged bleeding, primarily affect men. Hemophilia A is responsible for...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 001e238c-6a3e-5fdc-8eea-0b7232d7dd9f
DOI: 10.21203/rs.3.rs-5790537/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic Analysis of Factor VIII Gene Polymorphisms in Indian Populations for Hemophilia A Carrier ScreeningDOI 10.21203/rs.3.rs-5790537/v1Read

Analysis of Genotypes and Haplotypes of Factor VIII Gene Variants in Children with Hemophilia A from Northeast IndiaSemantic proximity Read

Molecular Characterization of Factor VIII Gene Variants in Hemophilia A: A Genotype-Haplotype Study from Eastern and Northern-Central India.Semantic proximity Read

Allele frequencies of three factor VIII gene polymorphisms in Iranian populations and their application in hemophilia A carrier detection.Semantic proximity Read

Carrier analysis and prenatal diagnosis of haemophilia A in North India.Semantic proximity Read

Utility of an exon 14 BslI polymorphism for improved genetic diagnosis of hemophilia A in Indian population.Semantic proximity Read

Evaluation of genetic markers linked to hemophilia A locus: an Indian experience.Semantic proximity Read

Remarkable variation in the informativeness of RFLP markers linked to hemophilia B locus in Indian population groups: implication in the strategy for carrier detection.Semantic proximity Read

Factor VIII and IX gene polymorphisms and carrier analysis in Indian population.Semantic proximity Read

Factor IX gene haplotypes and its relevance for the indirect genetic analysis of haemophilia B in its Indian perspective.Semantic proximity Read

Factor VIII gene mutations and RFLP analysis in hemophilia A.Semantic proximity Read

Use of Intron 1 and 22 inversions and linkage analysis in carrier detection of hemophilia A in Indians.Semantic proximity Read

Application of indirect linkage analysis and direct genotyping to hemophilia A carrier detection in Sichuan, China.Semantic proximity Read