Article
Utility of an exon 14 BslI polymorphism for improved genetic diagnosis of hemophilia A in Indian population.
Prenatal diagnosis - 1 Oct 2008
Mukundan Preethi, Shetty Shrimati, Kulkarni Bipin, Ghosh Kanjaksha
Abstract excerpt
BACKGROUND: Hemophilia A is a common X-linked recessive bleeding disorder caused by deleterious mutations in the gene encoding factor VIII. Though direct mutation analysis is the common practice in most of the developed countries, restriction fragment length polymorphism (RFLP) analysis using common polymorphic markers of factor VIII gene is still the most practical and feasible method in developing countries...
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