Factor VIII and IX gene polymorphisms and carrier analysis in Indian population.

doi:10.1002/(sici)1096-8652(199704)54:4<271::aid-ajh2>3.0.co;2-s

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Article

Factor VIII and IX gene polymorphisms and carrier analysis in Indian population.

American journal of hematology - 1 Apr 1997

Shetty S, Ghosh K, Pathare A, Colah R, Badakare S, Mohanty D

Abstract excerpt

The efficacy of the three common intra- and extragenic polymorphic sites of the factor VIII and IX genes has been examined in the Indian population, with an aim to develop a strategy that would be accurate and informative, yet economical. The approach for hemophilia A carrier detection includes tests for BclI, XbaI, and TaqI polymorphic sites for introns 18 and 22 and the extragenic locus St 14, respectively,...

Topics

Alleles
Factor IX
Factor VIII
Female
Genetic Carrier Screening
Hemophilia A
Hemophilia B
Humans
India
Male
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 9092680
DOI: 10.1002/(sici)1096-8652(199704)54:4<271::aid-ajh2>3.0.co;2-s

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