Article

Analysis of Genotypes and Haplotypes of Factor VIII Gene Variants in Children with Hemophilia A from Northeast India

2025-04-08

Abstract excerpt

<title>Abstract</title> <p><bold>Introduction: </bold>Hemophilia A, an X-linked recessive disorder caused by deficient factor VIII activity, affects 1 in 5,000 males globally and in northern India. This bleeding disorder results from quantitative or qualitative abnormalities in FVIII. Previous Indian studies emphasize the significance of intron polymorphisms (IVS7-SNP, Bcl-I, and Hind-III) for carrier detection t...

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Literature Corpus work: a572909f-79e2-569d-a7c5-d5a9014afa36
DOI: 10.21203/rs.3.rs-6381161/v1

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