Article
Correlation of histologic morphology and tumor stage with molecular genetic analysis using microdissection in gastric carcinomas.
Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Oct 1998
Sugai T, Habano W, Nakamura S, Yoshida T, Uesugi N, Suto T, Itoh C
Abstract excerpt
Precise correlation of histomorphology with the results of molecular genetic analysis is difficult in gastric cancer tissue composed of intestinal and diffuse types. A novel microdissection procedure was applied to correlate p53 and APC allelic loss with histologic type and tumor stage (mucosal vs. invasive cancer) in formalin-fixed, paraffin-embedded specimens of 25 gastric cancers. In addition, mucosal and...
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