Article
Genetic classification of intestinal-type and diffuse-type gastric cancers based on chromosomal loss and microsatellite instability.
Virchows Archiv : an international journal of pathology - 1 Oct 2003
Kim Kyoung-Mee, Kwon Mee-Sun, Hong Seung-Jin, Min Ki-Oak, Seo Eun-Joo, Lee Kyo-Young, Choi Sang-Wook, Rhyu Mun-Gan
Abstract excerpt
The stage of gastrointestinal cancers has been correlated with the loss of heterozygosity (LOH) and the presence of microsatellite instability (MSI). This study delineated the category of the extent of LOH and the presence of MSI for the genetic classification of the intestinal-type and diffuse-type gastric cancers that frequently exhibited intralesional heterogeneity. A total of 390 tumor foci from 116 gastric...
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