Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p300 gene alterations in intestinal and diffuse types of gastric carcinoma.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Jan 2004

Koshiishi Naoki, Chong Ja-Mun, Fukasawa Tomoki, Ikeno Rie, Hayashi Yukiko, Funata Nobuaki, Nagai Hideo, Miyaki Michiko, Matsumoto Yoshiro, Fukayama Masashi

Abstract excerpt

BACKGROUND: p300 is a transcriptional coactivator, and bi-allelic mutations of the p300 gene have been demonstrated in human cancers. METHODS: In 80 gastric carcinoma tissues, loss of heterozygosity (LOH) was analyzed by polymerase chain reaction (PCR) analysis, using 14 primer pairs at the 22q11-13 locus containing NF2 and p300. The mutations of the p300 gene were examined by reverse transcriptase-PCR (RT-PCR)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Tumor Suppressor

Share to Intestinal Neoplasms

Share to Loss of Heterozygosity

Share to Neoplasm Invasiveness

Share to Stomach Neoplasms

Share to Trans-Activators

Source

Identifiers

PMID: 15224194
DOI: 10.1007/s10120-004-0273-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p300 gene alterations in intestinal and diffuse types of gastric carcinoma.PMID 15224194Read ↗

p300 gene alterations in colorectal and gastric carcinomas.Semantic proximity Read ↗

Overexpression of p53 predicts shorter survival in diffuse type gastric cancer.Semantic proximity Read ↗

Molecular mechanisms involved in the pathogenesis of gastric carcinoma: interactions between genetic alterations, cellular phenotype and cancer histotype.Semantic proximity Read ↗

Mutation of ras oncogene in gastric adenocarcinoma: association with histological phenotype.Semantic proximity Read ↗

Immunohistochemical analysis of pRb2/p130, VEGF, EZH2, p53, p16INK4A, p27KIP1, p21WAF1, Ki‐67 expression patterns in gastric cancerSemantic proximity Read ↗

Intestinal and diffuse gastric cancers arise in a different background of Helicobacter pylori gastritis through different gene involvement.Semantic proximity Read ↗

Functional promoter polymorphisms of NFKB1 influence susceptibility to the diffuse type of gastric cancer.Semantic proximity Read ↗

Extensive intestinal metaplasia in gastric carcinoma and in other lesions requiring surgery: a study of 3,421 gastrectomy specimens from dwellers of the Atlantic and Pacific basins.Semantic proximity Read ↗

Inactivation of the E-cadherin gene in sporadic diffuse-type gastric cancer.Semantic proximity Read ↗

Interrelationship between chromosome 8 aneuploidy,C-MYCamplification and increased expression in individuals from northern Brazil with gastric adenocarcinomaSemantic proximity Read ↗

Overexpression of mutant p53 and c-erbB-2 proteins and mutations of the p15 and p16 genes in human gastric carcinoma: with respect to histological subtypes and stages.Semantic proximity Read ↗

Distinct promoter hypermethylation of p16INK4a, CDH1, and RAR-beta in intestinal, diffuse-adherent, and diffuse-scattered type gastric carcinomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.