Article
Preoperative genetic diagnosis of gastric carcinoma based on chromosomal loss and microsatellite instability.
International journal of cancer - 10 Jan 2005
Hong Seung-Jin, Choi Sang-Wook, Lee Kang-Hoon, Lee Sung, Min Ki-Ouk, Rhyu Mun-Gan
Abstract excerpt
The degree of chromosomal losses and the presence of microsatellite instability (MSI) in gastric carcinomas have been categorized into low-risk (low-level loss and MSI) and high-risk (baseline- and high-level losses) genotypes. With the aim of making a preoperative diagnosis, this study confirmed the stem line genotype that is common over an entire tumor as well as in a single biopsy specimen. Biopsy specimens...
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