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Article

Monoallelic methylation of the APC promoter is altered in normal gastric mucosa associated with neoplastic lesions.

Cancer research - 1 Oct 2004

Clément Geneviève, Bosman Fred T, Fontolliet Charlotte, Benhattar Jean

Abstract excerpt

Adenomatous polyposis coli (APC) promoter hypermethylation has been reported frequently in normal gastric mucosa, but it remained to be clarified whether this occurs in every individual. In this study, methylation of the APC promoter was analyzed in histologically normal-appearing gastric mucosa samples by methylation-sensitive single-strand conformation analysis and by a methylation-sensitive dot blot assay....

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Source

Identifiers

PMID: 15466175
DOI: 10.1158/0008-5472.CAN-03-2503

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Monoallelic methylation of the APC promoter is altered in normal gastric mucosa associated with neoplastic lesions.PMID 15466175Read ↗

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